Ashish Pandit

Ph.D. tech, visiting researcher from BBCE, Latvia

Biocompatible Regenerative Composite Scaffolds for Osteomyelitis Management

 

Supervisor: Prof. Dr.-Ing. habil. Aldo R. Boccaccini

The research project involves developing electrospun scaffolds to address osteomyelitis, a severe bone infection commonly associated with diabetic foot, fracture-related infections, and periprosthetic joint infections. The project involves utilization of derivatized chitosan, polyvinyl alcohol (PVA)/ polycaprolactone (PCL), and ion releasing bioactive glass for scaffold generation. Derivatized chitosan is proposed to enhance bone regeneration, possess antibacterial properties, and synergize with bioactive glass to combat resistant microbes like Staphylococcus Aureus. This approach is aimed to addresses infection, promote osteogenesis, and improve implant integration, providing a superior solution to current limitations in treating bone infections. The project is part of the research activities of the FAU Institute of Biomaterials in collaboration with the Baltic Biomaterials Center of Excellence (BBCE), a project that has received funding from the European Union’s Horizon 2020 Research and Innovation programme under grant agreement No 857287.