Julia Lemos de Oliveira

Doktorandin (in cotutelle with Federal University of Santa Catarina (UFSC), Brazil)

Advanced Fiber Wound Dressing via Melt Electro Writing for Treatment of Pressure Ulcers

 

Supervisors: Prof. Dr. Aldo Boccaccini (FAU), Prof. Dr. Claudia Sayer (UFSC), and Prof. Dr. Ana Paula S. I. Boemo (UFSC)

Pressure ulcers are chronic wounds that significantly impact patient quality of life and healthcare systems. This research aims to develop an advanced wound dressing using Melt Electro Writing (MEW) technology to optimize and accelerate the healing process. The dressing will combine biocompatible materials such as poly(caprolactone) (PCL) and other biodegradable polymers, offering a robust but biodegradable structure and functionalization capabilities through chemical reactions. Additionally, bioactive glass particles, modified with metallic ions or phytotherapeutic compounds, will be incorporated to stimulate angiogenesis, provide antimicrobial and anti-inflammatory effects, and enable controlled therapeutic release, expanding from previous research carried out at the FAU Institute of Biomaterials [1].

[1] A.-I. Damian-Buda, et al., Combining Mesoporous Bioactive Glass Nanoparticles (MBGNs) with Essential Oils to Tackle Bacterial Infection and Oxidative Stress for Bone Regeneration Applications, ACS Biomater. Sci. Eng. 10 (2024) 6860−6873.