Prof. Papia Haque

Alexander von Humboldt Fellow (Visiting researcher from University of Dhaka, Bangladesh)

Developing a correlation model between growth factors and ions released from bioactive glass in different stages of wound healing

Supervisor: Prof. Dr.-Ing. habil. Dr. h.c. Aldo R. Boccaccini

 Skin wound healing comprises a series of cell growth stimulation process and many bioactive mineral ions have already been identified as crucial for a number of biochemical reactions inside our body [1]. Electrospun fibrous scaffolds from different natural and synthetic polymers provide structural strength and large surface area to wound dressings [2]. The project will develop a model determining the relation between the concentration of ions released and the growth factors produced in the wound site with the healing progress. Relevant growth factors will be measured time to time after applying the wound dressing prepared on a 3D skin model. The proposed study is funded by the Alexander von Humboldt Foundation (Humboldt Research Fellowship Programme for Experienced Researchers).

References:

[1] Homaeigohar S, Li M, Boccaccini A R. Bioactive glass-based fibrous wound dressings. Burns & Trauma, 2022, 10.

 [2] Mukta N A, Ahmed S, Chowdhury A M S, Tareq S M, Sajib A A, Bashar M S, Haque P. Effect of core–sheath bi-polymeric scaffolds fabricated from acid-soluble collagen and poly(lactic acid) derivatives on wound healing. J. Appl. Polym. Sci., 2024, 141(28). doi.org/10.1002/app.55636