Rezvan Azari

Title: A comparative study on two types of commonly used bioactive ceramics in multifunctional composite coating systems for metallic implants

Supervisor: Prof. Dr.-lng. habil. Aldo R. Boccaccini

 

The demographics of ageing populations coupled with a dramatic increase in human lifespan have led to much larger potential recipients of metallic implants. Biomedical coatings have played a key role in resolving functionality and biocompatibility issues of metallic implants. The principal objective of this project is to develop and characterize multifunctional composite coatings consisting of either bioactive glass or hydroxyapatite and a polymer constituent (chitosan) for Ti alloy through the effective and versatile EPD method [1, 2]. The biological performance of the coatings, in terms of the capability of osteogenesis, will be studied via a comparative approach. Antibacterial, (tribo)mechanical, and electrochemical characteristics of the coating systems are other parameters of interest to be investigated. This project is funded by the German Academic Exchange Service (DAAD).

 

[1] L. R. Rivera, A. Cochis, S. Biser, E. Canciani, S. Ferraris, L. Rimondini, and A. R. Boccaccini, “Antibacterial, pro-angiogenic and pro-osteointegrative zein-bioactive glass/copper based coatings for implantable stainless steel aimed at bone healing,” Bioactive Materials, vol. 6, no. 5, pp. 1479–1490, May 2021. https://doi.org/10.1016/j.bioactmat.2020.11.001

[2] Y. Ahmed, M. Yasir, and M. A. Ur Rehman, “Fabrication and Characterization of Zein/Hydroxyapatite Composite Coatings for Biomedical Applications,” Surfaces, vol. 3, no. 2, pp. 237–250, Jun. 2020. https://doi.org/10.3390/surfaces3020018